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GL18 White Tamper-Evident Child-Resistant Closure with Integrated Syringe Plug

GL18 white tamper-evident child-resistant closure with syringe plug, PEHD or PP/PELD. Fits all GL18 bottles 5ml–100ml. Syringe-withdrawal dosing. Ideal for paediatric medicines and oral liquids.
MOQ and lead time applies – Please contact us for further details

The GL18 White Tamper-Evident Child-Resistant Closure with Integrated Syringe Plug (GL18TECRCW-ISP) is the most comprehensively specified syringe plug closure in BlueSky’s GL18 range — combining three independent protective and dosing functions in a single cap assembly: a child-resistant opening mechanism preventing unsupervised access by young children, a tamper-evident ring providing visible first-open evidence at retail, and an integrated PELD syringe plug enabling accurate volume withdrawal using an oral dosing syringe. Manufactured in PEHD or PP with a PELD syringe plug insert — both cap body materials available under a single product code — this closure is designed for paediatric oral liquid medicines, licensed OTC pharmaceutical preparations, vitamin and mineral liquid supplements, and regulated nutraceutical formulations where child safety, retail tamper evidence, and accurate syringe-based volumetric dosing are all simultaneously required.

Syringe-withdrawal dosing delivers higher volumetric accuracy than drop counting — the user draws an exact volume into the barrel of a calibrated oral syringe rather than counting drops, where variability in bottle angle, liquid viscosity, and surface tension can meaningfully affect the actual volume delivered. The self-sealing PELD plug flexes to admit the syringe tip on insertion and reseals on withdrawal, maintaining closure integrity between doses. Each of the three functions operates independently within the assembly: the child-resistant mechanism governs access when the bottle is closed, the tamper-evident ring provides one-time first-open evidence, and the syringe plug governs how liquid is withdrawn during use. As part of the GL18 system (also known as NW18 or DIN168), the GL18TECRCW-ISP is fully interchangeable across all GL18 glass dropper bottles in the BlueSky range — 5ml to 100ml, in both amber and clear glass. Contact BlueSky to confirm stock availability, MOQ, child-resistant certification status, TE ring type, syringe compatibility, and material choice guidance before specifying.

Additional information

Material

PEHD or PP/PELD

Neck size

GL18

Three Independent Functions — Child Resistance, Tamper Evidence, Syringe Dosing

The GL18TECRCW-ISP combines child resistance, tamper evidence, and syringe-withdrawal dosing in one closure — each function operating independently without compromising the others. The child-resistant mechanism prevents unsupervised access by young children. The tamper-evident ring provides visible first-open evidence at retail. The syringe plug enables accurate volumetric dose withdrawal using an oral dosing syringe. For paediatric medicines and regulated oral liquid products where all three requirements must be met simultaneously, this closure provides a complete single-assembly solution without the need for multiple components or specification compromises.

 

Child-Resistant Mechanism — Paediatric Safety Priority

The child-resistant opening mechanism requires a specific combination of actions to open that young children are statistically unlikely to perform successfully, while remaining practical for adults. For paediatric oral liquid medicines and concentrated pharmaceutical preparations where accidental ingestion by children presents a serious safety risk, child-resistant packaging is both a clinical imperative and in most regulated markets a legal requirement. The combination of child resistance with syringe-based dosing is particularly appropriate for paediatric applications — the closure prevents unsupervised access while enabling the precise, safe administration method preferred for young children. Please contact BlueSky’s team to confirm the child-resistant certification status of this specific closure before specifying.

Integral Tamper-Evident Ring — Retail and Regulatory Assurance

The tamper-evident ring provides visible evidence of first opening — when the cap is opened for the first time the TE bridges break and the ring remains on the bottle neck, confirming to the consumer and regulator that the product has not been accessed prior to purchase. For licensed OTC pharmaceutical preparations and regulated healthcare liquids sold through pharmacy and retail channels, tamper evidence is both a consumer safety expectation and a standard regulatory requirement. Please contact BlueSky’s team to confirm the specific TE ring type for this closure before specifying.

Integrated Syringe Plug — Accurate Volume Withdrawal

The PELD syringe plug insert is a self-sealing device that allows an oral dosing syringe to be inserted directly through the plug and into the bottle, enabling the user to withdraw a precise measured volume rather than counting drops. The plug flexes to admit the syringe tip on insertion and reseals on withdrawal, maintaining the integrity of the closure between doses and preventing leakage or contamination during storage. For paediatric oral liquid medicines in particular, syringe-based dosing is the clinically preferred administration method — more accurate, safer, and more intuitive for caregivers than drop counting. Syringe compatibility must be confirmed with BlueSky’s team prior to production.

PEHD or PP Cap Body with PELD Syringe Plug

Available in either PEHD or PP for the cap body — both offered under a single product code — with a PELD syringe plug insert. PEHD and PP both offer broad chemical compatibility with aqueous oral liquid formulations, vitamin preparations, alcohol-based tinctures, and herbal extracts. PELD provides the flexibility required for the syringe plug to self-seal correctly around the syringe tip on insertion and withdrawal. Please contact BlueSky’s team to confirm which cap body material is most appropriate for your formulation and filling process, and to clarify any practical differences between the two options.

The Most Safety-Comprehensive Syringe Plug Closure in the GL18 Range

The GL18TECRCW-ISP sits at the top of the GL18 syringe plug closure hierarchy — providing more combined safety functionality than any other syringe plug configuration in the range. For products requiring only one or two of these functions, simpler GL18 syringe plug configurations are available: GL18W-ISP (no TE or CRC), GL18TEW-ISP and GL18TEWPP-ISP (TE only, differing materials). Contact BlueSky’s team to confirm the most appropriate specification for your product category and regulatory requirements.

  • Oral liquid supplements
  • OTC oral preparations
  • Homeopathic oral preparations
  • Concentrated nutraceutical formulations
  • Oral tinctures and herbel extracts
  • Veterinary oral liquids

 

Delivery & Returns

Orders for products in our ‘In Stock’ ranges will normally be delivered within two working days. Our product ranges labelled as ‘Product MOQ Applicable’ may be subject to a lead time which will be confirmed to you when we receive your order. For information relating to delivery charges, please refer to the ‘Is there a carriage charge?’ section in our FAQs page.

In some instances, goods can be returned. Please view our full refunds policy in our terms and conditions here: Terms & Conditions.

Core Product Range

We endeavour to hold continuous stock of this product. We expect to stock these ranges for a significant period of time in the future. This ensures you can build ranges around them and rely on their availability both now and in the coming years.

In Stock

We hold these products in our UK warehouses for you and they are available for rapid delivery.

Product MOQ Applicable

These products are not currently available from our UK held stock. However, we can supply you from our flexible and solid, global supply chain. Please note that there are minimum order quantities (MOQs) associated with this product, and lead times may vary depending on the quantity ordered. For more information on MOQs and lead times, please contact: sales@blueskysolutionsuk.com

Additionally, we can create bespoke products for you whether through colour, decoration, or bespoke tooling - to your specification. Our team of product experts will work with you to understand your requirements and place the necessary orders.

Delivery & Returns

Frequently Asked
Questions

Why is this closure particularly suited to paediatric oral liquid medicines?

Paediatric oral liquid medicines present two simultaneous packaging challenges — preventing unsupervised access by the child patient, and enabling accurate, safe dosing by a caregiver. The GL18TECRCW-ISP addresses both directly: the child-resistant mechanism prevents the child from opening the bottle unsupervised, while the syringe plug enables the caregiver to withdraw a precise measured volume using a calibrated oral syringe — the clinically preferred administration method for young children where drop counting introduces unacceptable dosing variability. Tamper evidence provides the additional retail assurance expected for licensed pharmaceutical products sold through pharmacy channels.

How do the three functions interact during first use and subsequent doses?

On first purchase, the caregiver opens the closure using the child-resistant mechanism — breaking the tamper-evident bridges in the process, confirming the product has not been accessed previously. An oral dosing syringe is inserted through the syringe plug to withdraw the required dose volume, then removed — the plug reseals on withdrawal. On reclosing, the child-resistant mechanism re-engages, preventing unsupervised access on subsequent openings. This sequence repeats for every dose throughout the product’s life, with child resistance active at all times when the bottle is closed.

Does this closure meet child-resistant packaging regulatory requirements?

The GL18TECRCW-ISP features a child-resistant mechanism designed to prevent access by young children. For licensed pharmaceutical products, paediatric medicines, and other regulated applications where child-resistant packaging is a legal requirement, please contact BlueSky’s team to confirm the certification status of this closure before specifying. Your regulatory advisor can confirm the applicable packaging legislation for your product category and market.

What is the difference between this closure and the GL18TEW-ISP?

Both closures combine a tamper-evident ring with an integrated syringe plug delivering the same syringe-withdrawal dosing function, but the GL18TECRCW-ISP additionally incorporates a child-resistant opening mechanism. The GL18TEW-ISP is appropriate for retail oral liquid supplements and healthcare preparations where tamper evidence and syringe dosing are required but child-resistant packaging is not mandated for the product category. The GL18TECRCW-ISP is the correct specification where all three functions — child resistance, tamper evidence, and syringe-based dosing — are simultaneously required, as is typically the case for licensed paediatric oral liquid medicines and concentrated pharmaceutical preparations.

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